These drugs are indirect DNA-interacting agents . examples are :
1. deoxycoformycin (pentostatin) ^
2. 6-mercaptopurine ^
3. 6-thioguanine ^
4. azathioprine ^
5. 2-chlorodeoxy adenosine (cladribine) ^
6. fludarabine phosphate ^
7. asparaginase
8. hydroxy urea
9. capacitabine "
10. cytosine arabinoside "
11. azacytidine "
12. gemcitabine "
13. 5-fluorouracil "
14. methotrexate ~
15. pemetrexed ~
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^ (1-6) Purine analogs and related inhibitors .
" (9-13) Pyramidine analogs
~ (14,15) Folic acid analogs
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