Sunday, July 7, 2013

44 - Antimetabolites drugs ( Anticancer drugs )

These drugs are indirect DNA-interacting agents . examples are :


1. deoxycoformycin (pentostatin) ^

2. 6-mercaptopurine ^

3. 6-thioguanine ^

4. azathioprine ^

5. 2-chlorodeoxy adenosine (cladribine) ^

6. fludarabine phosphate ^

7. asparaginase
8. hydroxy urea
9. capacitabine "

10. cytosine arabinoside "

11. azacytidine "

12. gemcitabine "

13. 5-fluorouracil "

14. methotrexate ~

15. pemetrexed ~
---------------------------------
^ (1-6) Purine analogs and related inhibitors .
" (9-13) Pyramidine analogs
~ (14,15) Folic acid analogs 


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