43 - Antitumor antibiotics ( Anticancer agents )

These drugs are also direct DNA-interacting agents . examples are :


1. bleomycin
2. actinomycin D
3. mitomycin C
4. etoposide ( VP16-213 )
5. topotecan
6. irinotecan ( CPT II )
7. doxorubicin and daunorubicin
8. idarubicin
9. epirubicin
10. mitoxantrone

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45 - Antimitotic agents ( Anticancer drugs )

These drugs are also indirect DNA-interacting agents . examples are :


1. vincristine
2. vinblastine
3. vinorelbine
4. paclitaxel
5. docetaxel
6. etramustine phosphate
7. NAB-paclitaxel ( protein bound )

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57 - Anti-arrhythmic agents classification

Ia
QuinidineProcainamideDisopyramideIb
LidocainePhenytoinMexiletineIc
FlecainidePropafenoneMoricizineII
PropranololEsmololTimololMetoprololAtenololIII
AmiodaroneSotalolIbutilideDofetilideE-4031

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42 - Alkylating agents ( Anticancer drugs )

These drugs are direct DNA-interacting agents . examples are :


1. cyclophosphamide*
2. mechlorethamine*
3. chlorambucil*
4. melphalan(L-sarcolysin)*
5. ifosfamide*
 

6. lomustine ( CCNU ) %

7. carmustine ( BCNU ) %

8. streptozocin (streptozotocin) %


9. dacarbazine ( DTIC; dimethyltriazenoimidazole carboxamide ) =

10. temozolomide =


11. oxaliplatin -
12. cisplatin -
13. carboplatin -

14. altretamine ( formerly hexamethyl melamine ) +
15. thiotepa + 

16. procarbazine (N-methyl hydrazine, MIH) !

17. busulfan $
 -----------------------------

* (1-5) Nitrogen mustards 
%  (6-8) Nitrosoureas
=  (9,10) Triazenes
-  (11-13) Platinum coordination complexes
+ (14,15) Ethyleneimines and methylmelamines
! (16) Methylhydrazine derivative
$ (17) Alkyl sulfonate

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